SLC25A12

GENE INFORMATION

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Gene name

SLC25A12 (HGNC Symbol)

Synonyms

Aralar

Description

Solute carrier family 25 (aspartate/glutamate carrier), member 12 (HGNC Symbol)

Entrez gene summary

This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in this gene may also be a cause of global cerebral hypomyelination. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012]

Chromosome

2

Cytoband

q31.1

Chromosome location (bp)

172640880 - 172864766

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000115840 (version 75.37)

Entrez gene

8604

UniProt

O75746 (UniProt - Evidence at protein level)

neXtProt

NX_O75746

Antibodypedia

SLC25A12 antibodies
 

PROTEIN VIEW

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SLC25A12-001
 
SLC25A12-003
 
SLC25A12-006
 
SLC25A12-007
 
SLC25A12-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC25A12-001 ENSP00000388658
ENST00000422440
O75746
Show all »
Show » Show » 678 74.8 No 0
SLC25A12-003 ENSP00000437845
ENST00000475360
H0YFB2
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Show » Show » 175 19.9 No 0
SLC25A12-006 ENSP00000263812
ENST00000263812
F8W9J0
Show all »
Show » 87 10.1 No 0
SLC25A12-007 ENSP00000413968
ENST00000426896
B4DGK6
Show all »
Show » Show » 210 23.7 No 1
SLC25A12-201 ENSP00000376371
ENST00000392592
B3KR64
Show all »
Show » Show » 571 62.7 No 0