Splice variant |
Ensembl |
UniProt |
Protein class |
Gene ontology |
Length (aa) |
Molecular mass (kDa) |
Signal peptide (predicted) |
Transmembrane regions (predicted)
|
NFE2L2-001 |
ENSP00000380252
ENST00000397062
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Q16236 Show all »
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Q16236 [Direct mapping]Nuclear factor erythroid 2-related factor 2 C9J1A8 [Target identity:46%; Query identity:100%]Nuclear factor erythroid 2-related factor 2 C9J0Y1 [Target identity:38%; Query identity:100%]Nuclear factor erythroid 2-related factor 2 K7ER33 [Target identity:24%; Query identity:100%]Nuclear factor erythroid 2-related factor 2 Q9BZF8 [Target identity:4%; Query identity:100%]NF-E2-related factor 2
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COSMIC Missense Mutations COSMIC Somatic Mutations Transcription factors Basic domains Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes Protein evidence (Ezkurdia et al 2014)
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GO:0000785 [chromatin] GO:0001102 [RNA polymerase II activating transcription factor binding] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005813 [centrosome] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0010499 [proteasomal ubiquitin-independent protein catabolic process] GO:0016567 [protein ubiquitination] GO:0019904 [protein domain specific binding] GO:0030194 [positive regulation of blood coagulation] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0034599 [cellular response to oxidative stress] GO:0036003 [positive regulation of transcription from RNA polymerase II promoter in response to stress] GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process] GO:0043565 [sequence-specific DNA binding] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0045995 [regulation of embryonic development] GO:0060548 [negative regulation of cell death] GO:0070301 [cellular response to hydrogen peroxide] GO:0071356 [cellular response to tumor necrosis factor] GO:0071499 [cellular response to laminar fluid shear stress] GO:1902176 [negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress] GO:2000121 [regulation of removal of superoxide radicals] GO:2000352 [negative regulation of endothelial cell apoptotic process] GO:2000379 [positive regulation of reactive oxygen species metabolic process]
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605 |
67.8 |
No |
0 |
NFE2L2-002 |
ENSP00000380253
ENST00000397063
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Q16236 Show all »
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Q16236 [Direct mapping]Nuclear factor erythroid 2-related factor 2 C9J1A8 [Target identity:47%; Query identity:100%]Nuclear factor erythroid 2-related factor 2 C9J0Y1 [Target identity:39%; Query identity:100%]Nuclear factor erythroid 2-related factor 2 K7ER33 [Target identity:24%; Query identity:100%]Nuclear factor erythroid 2-related factor 2
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COSMIC Missense Mutations COSMIC Somatic Mutations Transcription factors Basic domains Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes Protein evidence (Ezkurdia et al 2014)
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GO:0000785 [chromatin] GO:0001102 [RNA polymerase II activating transcription factor binding] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005813 [centrosome] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0010499 [proteasomal ubiquitin-independent protein catabolic process] GO:0016567 [protein ubiquitination] GO:0019904 [protein domain specific binding] GO:0030194 [positive regulation of blood coagulation] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0034599 [cellular response to oxidative stress] GO:0036003 [positive regulation of transcription from RNA polymerase II promoter in response to stress] GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0045995 [regulation of embryonic development] GO:0060548 [negative regulation of cell death] GO:0070301 [cellular response to hydrogen peroxide] GO:0071356 [cellular response to tumor necrosis factor] GO:0071499 [cellular response to laminar fluid shear stress] GO:1902176 [negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress] GO:2000121 [regulation of removal of superoxide radicals] GO:2000352 [negative regulation of endothelial cell apoptotic process] GO:2000379 [positive regulation of reactive oxygen species metabolic process]
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589 |
66.1 |
No |
0 |
NFE2L2-003 |
ENSP00000467401
ENST00000464747
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Q16236 Show all »
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Q16236 [Direct mapping]Nuclear factor erythroid 2-related factor 2 C9J1A8 [Target identity:47%; Query identity:100%]Nuclear factor erythroid 2-related factor 2 C9J0Y1 [Target identity:39%; Query identity:100%]Nuclear factor erythroid 2-related factor 2 K7ER33 [Target identity:24%; Query identity:100%]Nuclear factor erythroid 2-related factor 2
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COSMIC Missense Mutations COSMIC Somatic Mutations Transcription factors Basic domains Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes Protein evidence (Ezkurdia et al 2014)
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Show »
« Hide
GO:0000785 [chromatin] GO:0001102 [RNA polymerase II activating transcription factor binding] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005813 [centrosome] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0010499 [proteasomal ubiquitin-independent protein catabolic process] GO:0016567 [protein ubiquitination] GO:0019904 [protein domain specific binding] GO:0030194 [positive regulation of blood coagulation] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0034599 [cellular response to oxidative stress] GO:0036003 [positive regulation of transcription from RNA polymerase II promoter in response to stress] GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0045995 [regulation of embryonic development] GO:0060548 [negative regulation of cell death] GO:0070301 [cellular response to hydrogen peroxide] GO:0071356 [cellular response to tumor necrosis factor] GO:0071499 [cellular response to laminar fluid shear stress] GO:1902176 [negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress] GO:2000121 [regulation of removal of superoxide radicals] GO:2000352 [negative regulation of endothelial cell apoptotic process] GO:2000379 [positive regulation of reactive oxygen species metabolic process]
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589 |
66.1 |
No |
0 |
NFE2L2-006 |
ENSP00000410015
ENST00000423513
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C9JFL6 Show all »
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C9JFL6 [Target identity:100%; Query identity:100%]Nuclear factor erythroid 2-related factor 2
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COSMIC Missense Mutations COSMIC Somatic Mutations Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes Protein evidence (Ezkurdia et al 2014)
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|
141 |
16.9 |
No |
0 |
NFE2L2-008 |
ENSP00000411575
ENST00000446151
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Q16236 Show all »
« Hide
Q16236 [Direct mapping]Nuclear factor erythroid 2-related factor 2
|
Show »
« Hide
COSMIC Missense Mutations COSMIC Somatic Mutations Transcription factors Basic domains Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes Protein evidence (Ezkurdia et al 2014)
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Show »
« Hide
GO:0000785 [chromatin] GO:0001102 [RNA polymerase II activating transcription factor binding] GO:0003677 [DNA binding] GO:0003700 [sequence-specific DNA binding transcription factor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005813 [centrosome] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0010499 [proteasomal ubiquitin-independent protein catabolic process] GO:0016567 [protein ubiquitination] GO:0019904 [protein domain specific binding] GO:0030194 [positive regulation of blood coagulation] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036003 [positive regulation of transcription from RNA polymerase II promoter in response to stress] GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0045995 [regulation of embryonic development] GO:0070301 [cellular response to hydrogen peroxide] GO:0071356 [cellular response to tumor necrosis factor] GO:0071499 [cellular response to laminar fluid shear stress] GO:1902176 [negative regulation of intrinsic apoptotic signaling pathway in response to oxidative stress] GO:2000121 [regulation of removal of superoxide radicals] GO:2000352 [negative regulation of endothelial cell apoptotic process] GO:2000379 [positive regulation of reactive oxygen species metabolic process]
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582 |
65.4 |
No |
0 |
NFE2L2-009 |
ENSP00000412191
ENST00000421929
|
C9J0Y1 Show all »
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C9J0Y1 [Target identity:100%; Query identity:100%]Nuclear factor erythroid 2-related factor 2 K7ER33 [Target identity:62%; Query identity:100%]Nuclear factor erythroid 2-related factor 2
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COSMIC Missense Mutations COSMIC Somatic Mutations Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes Protein evidence (Ezkurdia et al 2014)
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|
234 |
26.7 |
No |
0 |
NFE2L2-010 |
ENSP00000391291
ENST00000430047
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C9J3K4 Show all »
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C9J3K4 [Target identity:100%; Query identity:100%]Nuclear factor erythroid 2-related factor 2
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COSMIC Missense Mutations COSMIC Somatic Mutations Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes Protein evidence (Ezkurdia et al 2014)
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68 |
7.6 |
No |
0 |
NFE2L2-012 |
ENSP00000391590
ENST00000449627
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C9JBM0 Show all »
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C9JBM0 [Target identity:100%; Query identity:100%]Nuclear factor erythroid 2-related factor 2
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COSMIC Missense Mutations COSMIC Somatic Mutations Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes Protein evidence (Ezkurdia et al 2014)
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Show »
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|
265 |
30.2 |
No |
0 |
NFE2L2-013 |
ENSP00000400073
ENST00000448782
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C9J1A8 Show all »
« Hide
C9J1A8 [Target identity:100%; Query identity:100%]Nuclear factor erythroid 2-related factor 2 C9J0Y1 [Target identity:83%; Query identity:100%]Nuclear factor erythroid 2-related factor 2 K7ER33 [Target identity:52%; Query identity:100%]Nuclear factor erythroid 2-related factor 2
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Show »
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COSMIC Missense Mutations COSMIC Somatic Mutations Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes Protein evidence (Ezkurdia et al 2014)
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Show »
« Hide
|
280 |
31.7 |
No |
0 |
NFE2L2-014 |
ENSP00000416308
ENST00000458603
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H7C498 Show all »
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H7C498 [Target identity:100%; Query identity:100%]Nuclear factor erythroid 2-related factor 2
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Show »
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COSMIC Missense Mutations COSMIC Somatic Mutations Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes Protein evidence (Ezkurdia et al 2014)
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47 |
5.4 |
No |
0 |
NFE2L2-015 |
ENSP00000468089
ENST00000588123
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K7ER33 Show all »
« Hide
K7ER33 [Target identity:100%; Query identity:100%]Nuclear factor erythroid 2-related factor 2
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Show »
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COSMIC Missense Mutations COSMIC Somatic Mutations Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes Protein evidence (Ezkurdia et al 2014)
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Show »
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|
146 |
16.9 |
No |
0 |
NFE2L2-016 |
ENSP00000464920
ENST00000586532
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K7EIW5 Show all »
« Hide
K7EIW5 [Target identity:100%; Query identity:100%]Nuclear factor erythroid 2-related factor 2 C9J0Y1 [Target identity:88%; Query identity:100%]Nuclear factor erythroid 2-related factor 2 K7ER33 [Target identity:55%; Query identity:100%]Nuclear factor erythroid 2-related factor 2
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Show »
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COSMIC Missense Mutations COSMIC Somatic Mutations Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes Protein evidence (Ezkurdia et al 2014)
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Show »
« Hide
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265 |
30.1 |
No |
0 |