PTCH2

GENE INFORMATION

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Gene name

PTCH2

Synonyms

Description

Patched 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a transmembrane receptor of the patched gene family. The encoded protein may function as a tumor suppressor in the hedgehog signaling pathway. Alterations in this gene have been associated with nevoid basal cell carcinoma syndrome, basal cell carcinoma, medulloblastoma, and susceptibility to congenital macrostomia. Alternatively spliced transcript variants have been described.[provided by RefSeq, Oct 2009]

Chromosome

1

Cytoband

p34.1

Chromosome location (bp)

45285516 - 45308735

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000117425 (version 75.37)

Entrez gene

8643

UniProt

Q9Y6C5 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9Y6C5

Antibodypedia

PTCH2 antibodies
 

PROTEIN VIEW

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PTCH2-001
 
PTCH2-002
 
PTCH2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PTCH2-001 ENSP00000361266
ENST00000372192
Q9Y6C5
Show all »
Show » Show » 1203 130.5 No >9
PTCH2-002 ENSP00000413169
ENST00000438067
Show » 88 9.7 No 0
PTCH2-201 ENSP00000389703
ENST00000447098
Q9Y6C5
Show all »
Show » Show » 1146 124.9 No >9