PRDX1

GENE INFORMATION

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Gene name

PRDX1 (HGNC Symbol)

Synonyms

NKEFA, PAGA

Description

Peroxiredoxin 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011]

Chromosome

1

Cytoband

p34.1

Chromosome location (bp)

45976708 - 45988719

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000117450 (version 75.37)

Entrez gene

5052

UniProt

Q06830 (UniProt - Evidence at protein level)

neXtProt

NX_Q06830

Antibodypedia

PRDX1 antibodies
 

PROTEIN VIEW

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PRDX1-001
 
PRDX1-002
 
PRDX1-003
 
PRDX1-004
 
PRDX1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRDX1-001 ENSP00000361152
ENST00000319248
Q06830
Show all »
Show » Show » 199 22.1 No 0
PRDX1-002 ENSP00000407034
ENST00000447184
Show » Show » 171 19 No 0
PRDX1-003 ENSP00000361150
ENST00000372079
Show » Show » 97 10.7 No 0
PRDX1-004 ENSP00000389047
ENST00000424390
Show » Show » 171 19 No 0
PRDX1-201 ENSP00000262746
ENST00000262746
Q06830
Show all »
Show » Show » 199 22.1 No 0