PROX1

GENE INFORMATION

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Gene name

PROX1

Synonyms

Description

Prospero homeobox 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Chromosome

1

Cytoband

q32.3

Chromosome location (bp)

214156524 - 214214595

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000117707 (version 75.37)

Entrez gene

5629

UniProt

Q92786 (UniProt - Evidence at protein level)

neXtProt

NX_Q92786

Antibodypedia

PROX1 antibodies
 

PROTEIN VIEW

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PROX1-001
 
PROX1-002
 
PROX1-004
 
PROX1-006
 
PROX1-201
 
PROX1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PROX1-001 ENSP00000355925
ENST00000366958
Q92786
Show all »
Show » Show » 737 83.2 No 0
PROX1-002 ENSP00000420283
ENST00000498508
Q92786
Show all »
Show » Show » 737 83.2 No 0
PROX1-004 ENSP00000419517
ENST00000471129
C9JU29
Show all »
Show » Show » 230 25.8 No 0
PROX1-006 ENSP00000475357
ENST00000607425
U3KPY6
Show all »
Show » Show » 143 15.6 No 0
PROX1-201 ENSP00000261454
ENST00000261454
Q92786
Show all »
Show » Show » 737 83.2 No 0
PROX1-202 ENSP00000400694
ENST00000435016
Q92786
Show all »
Show » Show » 737 83.2 No 0