KLF12

GENE INFORMATION

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Gene name

KLF12 (HGNC Symbol)

Synonyms

AP-2rep, AP2REP, HSPC122

Description

Kruppel-like factor 12 (HGNC Symbol)

Entrez gene summary

Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

13

Cytoband

q22.1

Chromosome location (bp)

74260226 - 74708394

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000118922 (version 75.37)

Entrez gene

11278

UniProt

Q9Y4X4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y4X4

Antibodypedia

KLF12 antibodies
 

PROTEIN VIEW

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KLF12-001
 
KLF12-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KLF12-001 ENSP00000366897
ENST00000377669
Q9Y4X4
Show all »
Show » Show » 402 44.2 No 0
KLF12-201 ENSP00000366894
ENST00000377666
Q9Y4X4
Show all »
Show » Show » 402 44.2 No 0