MSX2

TISSUE ATLAS

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Gene description

Msh homeobox 2

RNA tissue category

Tissue enhanced (placenta, urinary bladder).

Protein summary

Detected at High or Medium expression level in 29 of 73 analyzed normal tissue cell types.

Protein expression

Strong nuclear immunoreactivity was observed in the thyroid gland and subsets of cells of lymphoid cells. Strong cytoplasmic staining was observed in gastric parietal cells and distal renal tubuli. Liver, muscle cells and several squamous epithelia were negative. Remaining normal tissues displayed weak to moderate positivity, mainly nuclear.

Protein class

Disease related genes, Plasma proteins, Transcription factors

Predicted localization

Intracellular

Protein evidence

Evidence at protein level

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Placenta
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

100
50
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus N/A
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA005652