MRC1

GENE INFORMATION

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Gene name

MRC1 (HGNC Symbol)

Synonyms

bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1

Description

Mannose receptor, C type 1 (HGNC Symbol)

Entrez gene summary

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Apr 2011]

Chromosome

10

Cytoband

p12.33

Chromosome location (bp)

18098352 - 18200091

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000120586 (version 75.37)

Entrez gene

4360

UniProt

P22897 (UniProt - Evidence at protein level)

neXtProt

NX_P22897

Antibodypedia

MRC1 antibodies
 

PROTEIN VIEW

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MRC1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRC1-001 ENSP00000239761
ENST00000239761
P22897
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