ETF1

GENE INFORMATION

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Gene name

ETF1 (HGNC Symbol)

Synonyms

ERF, ERF1, RF1, SUP45L1, TB3-1

Description

Eukaryotic translation termination factor 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X. [provided by RefSeq, Aug 2013]

Chromosome

5

Cytoband

q31.2

Chromosome location (bp)

137841784 - 137878989

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000120705 (version 75.37)

Entrez gene

2107

UniProt

P62495 (UniProt - Evidence at protein level)

neXtProt

NX_P62495

Antibodypedia

ETF1 antibodies
 

PROTEIN VIEW

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ETF1-001
 
ETF1-002
 
ETF1-003
 
ETF1-006
 
ETF1-008
 
ETF1-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ETF1-001 ENSP00000353741
ENST00000360541
P62495
Show all »
Show » Show » 437 49 No 0
ETF1-002 ENSP00000421288
ENST00000499810
Q96CG1
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Show » Show » 404 45.5 No 0
ETF1-003 ENSP00000422203
ENST00000503014
B7Z7P8
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Show » Show » 423 47.5 No 0
ETF1-006 ENSP00000425689
ENST00000507939
D6RJE8
Show all »
Show » Show » 120 13.3 No 0
ETF1-008 ENSP00000422272
ENST00000512198
D6RCB3
Show all »
Show » Show » 95 10.5 No 0
ETF1-009 ENSP00000461082
ENST00000572514
I3L492
Show all »
Show » Show » 208 22.9 No 0