COIL

GENE INFORMATION

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Gene name

COIL (HGNC Symbol)

Synonyms

CLN80, p80-coilin

Description

Coilin (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q22

Chromosome location (bp)

55015548 - 55038415

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000121058 (version 75.37)

Entrez gene

8161

UniProt

P38432 (UniProt - Evidence at protein level)

neXtProt

NX_P38432

Antibodypedia

COIL antibodies
 

PROTEIN VIEW

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COIL-001
 
COIL-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

COIL-001 ENSP00000240316
ENST00000240316
P38432
Show all »
Show » Show » 576 62.6 No 0
COIL-002 ENSP00000460217
ENST00000573008
I3L369
Show all »
Show » 37 4.1 No 0