PTGFR

GENE INFORMATION

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Gene name

PTGFR (HGNC Symbol)

Synonyms

FP

Description

Prostaglandin F receptor (FP) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p31.1

Chromosome location (bp)

78769568 - 79005434

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000122420 (version 75.37)

Entrez gene

5737

UniProt

P43088 (UniProt - Evidence at protein level)

neXtProt

NX_P43088

Antibodypedia

PTGFR antibodies
 

PROTEIN VIEW

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PTGFR-001
 
PTGFR-002
 
PTGFR-003
 
PTGFR-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PTGFR-001 ENSP00000359793
ENST00000370757
P43088
Show all »
Show » Show » 359 40.1 No 7
PTGFR-002 ENSP00000359794
ENST00000370758
P43088
Show all »
Show » Show » 359 40.1 No 7
PTGFR-003 ENSP00000359792
ENST00000370756
P43088
Show all »
Show » Show » 297 33.7 No 6
PTGFR-004 ENSP00000432599
ENST00000497923
F2Z2Z6
Show all »
Show » Show » 297 33.5 No 6