RAMP3

GENE INFORMATION

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Gene name

RAMP3

Synonyms

Description

Receptor (G protein-coupled) activity modifying protein 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

p13

Chromosome location (bp)

45197390 - 45225901

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000122679 (version 75.37)

Entrez gene

10268

UniProt

O60896 (UniProt - Evidence at protein level)

neXtProt

NX_O60896

Antibodypedia

RAMP3 antibodies
 

PROTEIN VIEW

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RAMP3-001
 
RAMP3-002
 
RAMP3-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RAMP3-001 ENSP00000242249
ENST00000242249
O60896
Show all »
Show » Show » 148 16.5 Yes 1
RAMP3-002 ENSP00000419012
ENST00000481345
O60896
Show all »
Show » Show » 148 16.5 Yes 1
RAMP3-003 ENSP00000418460
ENST00000496212
J3KR56
Show all »
Show » Show » 151 16.8 Yes 1