MXD4

GENE INFORMATION

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Gene name

MXD4 (HGNC Symbol)

Synonyms

bHLHc12, MAD4, MST149, MSTP149

Description

MAX dimerization protein 4 (HGNC Symbol)

Entrez gene summary

This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq, Jul 2008]

Chromosome

4

Cytoband

p16.3

Chromosome location (bp)

2249159 - 2264021

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000123933 (version 75.37)

Entrez gene

10608

UniProt

Q14582 (UniProt - Evidence at transcript level)

neXtProt

NX_Q14582

Antibodypedia

MXD4 antibodies
 

PROTEIN VIEW

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MXD4-001
 
MXD4-004
 
MXD4-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MXD4-001 ENSP00000337889
ENST00000337190
Q14582
Show all »
Show » Show » 209 23.5 No 0
MXD4-004 ENSP00000421209
ENST00000510822
D6RGV1
Show all »
107 12 No 0
MXD4-006 ENSP00000422660
ENST00000513380
82 9 No 0