FASTKD3

GENE INFORMATION

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Gene name

FASTKD3 (HGNC Symbol)

Synonyms

FLJ23274, MGC5297

Description

FAST kinase domains 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue. Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Chromosome

5

Cytoband

p15.31

Chromosome location (bp)

7859272 - 7869150

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000124279 (version 75.37)

Entrez gene

79072

UniProt

Q14CZ7 (UniProt - Evidence at transcript level)

neXtProt

NX_Q14CZ7

Antibodypedia

FASTKD3 antibodies
 

PROTEIN VIEW

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FASTKD3-001
 
FASTKD3-002
 
FASTKD3-004
 
FASTKD3-006
 
FASTKD3-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FASTKD3-001 ENSP00000264669
ENST00000264669
Q14CZ7
Show all »
Show » Show » 662 75.7 No 0
FASTKD3-002 ENSP00000424568
ENST00000511261
D6RB04
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Show » 57 6.8 No 0
FASTKD3-004 ENSP00000421798
ENST00000507036
D6RAR6
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Show » Show » 608 69.4 No 0
FASTKD3-006 ENSP00000426008
ENST00000504695
D6RHY4
Show all »
Show » 245 27.6 No 0
FASTKD3-007 ENSP00000422443
ENST00000507572
D6RC07
Show all »
Show » 181 20.4 No 0