SCGB1D2

GENE INFORMATION

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Gene name

SCGB1D2 (HGNC Symbol)

Synonyms

LIPB, LPHB

Description

Secretoglobin, family 1D, member 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin gene products are widely expressed in normal tissues, especially in endocrine-responsive organs. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 10, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q12.3

Chromosome location (bp)

62009682 - 62012280

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000124935 (version 75.37)

Entrez gene

10647

UniProt

O95969 (UniProt - Evidence at transcript level)

neXtProt

NX_O95969

Antibodypedia

SCGB1D2 antibodies
 

PROTEIN VIEW

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SCGB1D2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SCGB1D2-001 ENSP00000244926
ENST00000244926
O95969
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