PAX8

GENE INFORMATION

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Gene name

PAX8

Synonyms

Description

Paired box 8 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]

Chromosome

2

Cytoband

q13

Chromosome location (bp)

113973574 - 114036527

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125618 (version 75.37)

Entrez gene

7849

UniProt

Q06710 (UniProt - Evidence at protein level)

neXtProt

NX_Q06710

Antibodypedia

PAX8 antibodies
 

PROTEIN VIEW

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PAX8-001
 
PAX8-002
 
PAX8-003
 
PAX8-004
 
PAX8-006
 
PAX8-008
 
PAX8-009
 
PAX8-012
 
PAX8-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PAX8-001 ENSP00000395498
ENST00000429538
Q06710
Show all »
Show » Show » 450 48.2 No 0
PAX8-002 ENSP00000263335
ENST00000263335
Q06710
Show all »
Show » Show » 321 34.9 No 0
PAX8-003 ENSP00000380768
ENST00000397647
Q06710
Show all »
Show » Show » 287 31 No 0
PAX8-004 ENSP00000314750
ENST00000348715
Q06710
Show all »
Show » Show » 398 43 No 0
PAX8-006 ENSP00000451240
ENST00000468980
Show » 173 18.5 No 0
PAX8-008 ENSP00000451618
ENST00000497038
Show » 2 0.1 No 0
PAX8-009 ENSP00000452547
ENST00000465084
Show » 98 9.9 No 0
PAX8-012 ENSP00000451213
ENST00000554830
G3V3F3
Show all »
Show » 31 3.4 No 0
PAX8-201 ENSP00000263334
ENST00000263334
Q06710
Show all »
Show » Show » 398 43 No 0