COX7C

GENE INFORMATION

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Gene name

COX7C

Synonyms

Description

Cytochrome c oxidase subunit VIIc (HGNC Symbol)

Entrez gene summary

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIc, which shares 87% and 85% amino acid sequence identity with mouse and bovine COX VIIc, respectively, and is found in all tissues. A pseudogene COX7CP1 has been found on chromosome 13. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q14.3

Chromosome location (bp)

85913721 - 85916779

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000127184 (version 75.37)

Entrez gene

1350

UniProt

P15954 (UniProt - Evidence at protein level)

neXtProt

NX_P15954

Antibodypedia

COX7C antibodies
 

PROTEIN VIEW

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COX7C-001
 
COX7C-002
 
COX7C-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

COX7C-001 ENSP00000247655
ENST00000247655
P15954
Show all »
Show » Show » 63 7.2 No 1
COX7C-002 ENSP00000425759
ENST00000509578
P15954
Show all »
Show » Show » 63 7.2 No 1
COX7C-006 ENSP00000422012
ENST00000515763
D6R9Z7
Show all »
Show » Show » 56 6.4 No 1