SPINK2

GENE INFORMATION

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Gene name

SPINK2 (HGNC Symbol)

Synonyms

HUSI-II

Description

Serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the family of serine protease inhibitors of the Kazal type (SPINK). The encoded protein acts as a trypsin and acrosin inhibitor in the genital tract and is localized in the spermatozoa. The protein has been associated with the progression of lymphomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

Chromosome

4

Cytoband

q12

Chromosome location (bp)

57676026 - 57687908

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000128040 (version 75.37)

Entrez gene

6691

UniProt

P20155 (UniProt - Evidence at protein level)

neXtProt

NX_P20155

Antibodypedia

SPINK2 antibodies
 

PROTEIN VIEW

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SPINK2-001
 
SPINK2-002
 
SPINK2-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SPINK2-001 ENSP00000248701
ENST00000248701
P20155
Show all »
Show » Show » 84 9.3 Yes 0
SPINK2-002 ENSP00000425961
ENST00000506738
D6RI10
Show all »
Show » Show » 134 13.9 Yes 0
SPINK2-003 ENSP00000423858
ENST00000504762
D6RC51
Show all »
Show » Show » 119 12.5 Yes 0