POT1

GENE INFORMATION

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Gene name

POT1 (HGNC Symbol)

Synonyms

DKFZp586D211, hPot1

Description

Protection of telomeres 1 (HGNC Symbol)

Entrez gene summary

This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

q31.33

Chromosome location (bp)

124462440 - 124570037

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000128513 (version 75.37)

Entrez gene

25913

UniProt

Q9NUX5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NUX5

Antibodypedia

POT1 antibodies
 

PROTEIN VIEW

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 « 
 
POT1-001
 
POT1-003
 
POT1-006
 
POT1-008
 
POT1-009
 
POT1-010
 
POT1-011
 
POT1-012
 
POT1-013
 
POT1-014
 
POT1-016
 
POT1-019
 
POT1-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

POT1-001 ENSP00000350249
ENST00000357628
Q9NUX5
Show all »
Show » Show » 634 71.4 No 0
POT1-003 ENSP00000388921
ENST00000446993
C9JPG9
Show all »
Show » Show » 82 9.2 No 0
POT1-006 ENSP00000403088
ENST00000429326
Q5MJ33
Show all »
Show » 45 4.9 No 0
POT1-008 ENSP00000416820
ENST00000436534
Show » 138 15.4 No 0
POT1-009 ENSP00000397632
ENST00000430927
Show » 85 9.5 No 0
POT1-010 ENSP00000476290
ENST00000487564
Show » 77 9 No 0
POT1-011 ENSP00000476506
ENST00000607932
Q5MJ34
Show all »
Show » Show » 518 58.4 No 0
POT1-012 ENSP00000476371
ENST00000608057
Q5MJ35
Show all »
Show » Show » 340 38 No 0
POT1-013 ENSP00000477258
ENST00000609702
Show » Show » 73 8.1 No 0
POT1-014 ENSP00000476673
ENST00000610141
Show » 119 13.3 No 0
POT1-016 ENSP00000477320
ENST00000608200
Show » 86 9.7 No 0
POT1-019 ENSP00000476981
ENST00000609106
B7Z7M5
Show all »
Show » Show » 580 65 No 0
POT1-201 ENSP00000377002
ENST00000393329
A8MTK3
Show all »
Show » Show » 503 56.8 No 0