HAT1

GENE INFORMATION

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Gene name

HAT1 (HGNC Symbol)

Synonyms

KAT1

Description

Histone acetyltransferase 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2009]

Chromosome

2

Cytoband

q31.1

Chromosome location (bp)

172778958 - 172848599

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000128708 (version 75.37)

Entrez gene

8520

UniProt

O14929 (UniProt - Evidence at protein level)

neXtProt

NX_O14929

Antibodypedia

HAT1 antibodies
 

PROTEIN VIEW

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HAT1-001
 
HAT1-002
 
HAT1-003
 
HAT1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HAT1-001 ENSP00000264108
ENST00000264108
O14929
Show all »
Show » Show » 419 49.5 No 0
HAT1-002 ENSP00000407921
ENST00000412731
F8WEW1
Show all »
Show » 46 5.2 No 0
HAT1-003 ENSP00000403466
ENST00000457761
F8W9G7
Show all »
Show » Show » 125 15 No 0
HAT1-201 ENSP00000376363
ENST00000392584
O14929
Show all »
Show » Show » 334 39.8 No 0