HOXD11

GENE INFORMATION

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Gene name

HOXD11 (HGNC Symbol)

Synonyms

HOX4, HOX4F

Description

Homeobox D11 (HGNC Symbol)

Entrez gene summary

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The product of the mouse Hoxd11 gene plays a role in forelimb morphogenesis. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q31.1

Chromosome location (bp)

176968944 - 176974722

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000128713 (version 75.37)

Entrez gene

3237

UniProt

P31277 (UniProt - Evidence at transcript level)

neXtProt

NX_P31277

Antibodypedia

HOXD11 antibodies
 

PROTEIN VIEW

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HOXD11-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HOXD11-001 ENSP00000249504
ENST00000249504
P31277
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