GDF2

GENE INFORMATION

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Gene name

GDF2 (HGNC Symbol)

Synonyms

BMP-9, BMP9

Description

Growth differentiation factor 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. [provided by RefSeq, Jan 2014]

Chromosome

10

Cytoband

q11.22

Chromosome location (bp)

48413092 - 48416853

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000128802 (version 75.37)

Entrez gene

2658

UniProt

Q9UK05 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UK05

Antibodypedia

GDF2 antibodies
 

PROTEIN VIEW

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GDF2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GDF2-001 ENSP00000249598
ENST00000249598
Q9UK05
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