ANGPTL3

TISSUE ATLAS

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Gene description

Angiopoietin-like 3

RNA tissue category

Tissue enriched (liver).

Protein summary

Detected at High or Medium expression level in 17 of 82 analyzed normal tissue cell types.

Protein expression

Hepatocytes and smooth muscle cells displayed strong cytoplasmic positivity. Respiratory epithelia, small intestine, adrenal cortex, renal tubules, cerebellum and heart myocytes showed moderate staining. Neuropil showed distinct positivity. Other normal tissues were weakly stained or negative.

Protein class

Disease related genes, Plasma proteins, Predicted secreted proteins

Predicted localization

Secreted

Protein evidence

Evidence at protein level

Protein reliability

Supportive based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

400
200
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA038097