CHI3L1

GENE INFORMATION

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Gene name

CHI3L1 (HGNC Symbol)

Synonyms

GP39, YKL40

Description

Chitinase 3-like 1 (cartilage glycoprotein-39) (HGNC Symbol)

Entrez gene summary

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling. [provided by RefSeq, Sep 2009]

Chromosome

1

Cytoband

q32.1

Chromosome location (bp)

203148059 - 203155877

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000133048 (version 75.37)

Entrez gene

1116

UniProt

P36222 (UniProt - Evidence at protein level)

neXtProt

NX_P36222

Antibodypedia

CHI3L1 antibodies
 

PROTEIN VIEW

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CHI3L1-001
 
CHI3L1-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CHI3L1-001 ENSP00000255409
ENST00000255409
P36222
Show all »
Show » Show » 383 42.6 Yes 0
CHI3L1-005 ENSP00000385350
ENST00000404436
Q9NY41
Show all »
Show » Show » 152 16.7 No 0