NTS

GENE INFORMATION

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Gene name

NTS

Synonyms

Description

Neurotensin (HGNC Symbol)

Entrez gene summary

This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active. [provided by RefSeq, Oct 2014]

Chromosome

12

Cytoband

q21.31

Chromosome location (bp)

86268073 - 86276770

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000133636 (version 75.37)

Entrez gene

4922

UniProt

P30990 (UniProt - Evidence at protein level)

neXtProt

NX_P30990

Antibodypedia

NTS antibodies
 

PROTEIN VIEW

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NTS-001
 
NTS-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NTS-001 ENSP00000256010
ENST00000256010
P30990
Show all »
Show » Show » 170 19.8 Yes 0
NTS-002 ENSP00000448328
ENST00000551529
G3V1X6
Show all »
Show » Show » 95 11.2 Yes 0