KLRD1

GENE INFORMATION

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Gene name

KLRD1 (HGNC Symbol)

Synonyms

CD94

Description

Killer cell lectin-like receptor subfamily D, member 1 (HGNC Symbol)

Entrez gene summary

Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

p13.2

Chromosome location (bp)

10378657 - 10469850

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000134539 (version 75.37)

Entrez gene

3824

UniProt

Q13241 (UniProt - Evidence at protein level)

neXtProt

NX_Q13241

Antibodypedia

KLRD1 antibodies
 

PROTEIN VIEW

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KLRD1-001
 
KLRD1-002
 
KLRD1-004
 
KLRD1-005
 
KLRD1-006
 
KLRD1-007
 
KLRD1-012
 
KLRD1-201
 
KLRD1-202
 
KLRD1-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KLRD1-001 ENSP00000371332
ENST00000381907
Q13241
Show all »
Show » Show » 179 20.5 No 1
KLRD1-002 ENSP00000438669
ENST00000544747
F5H2B7
Show all »
Show » Show » 139 16 No 0
KLRD1-004 ENSP00000441074
ENST00000543420
F5GX94
Show all »
Show » 106 11.9 No 1
KLRD1-005 ENSP00000438514
ENST00000539374
F5GX94
Show all »
Show » 106 11.9 No 1
KLRD1-006 ENSP00000443584
ENST00000543777
F6WZH4
Show all »
Show » Show » 158 18.3 No 1
KLRD1-007 ENSP00000344858
ENST00000344825
E9PCX9
Show all »
Show » 72 8 No 0
KLRD1-012 ENSP00000437880
ENST00000539792
H0YFB8
Show all »
Show » 51 5.8 No 0
KLRD1-201 ENSP00000338130
ENST00000336164
Q13241
Show all »
Show » Show » 179 20.5 No 1
KLRD1-202 ENSP00000310929
ENST00000350274
Q13241
Show all »
Show » Show » 148 17.1 No 0
KLRD1-203 ENSP00000371333
ENST00000381908
Q13241
Show all »
Show » Show » 180 20.6 No 1