MTNR1B

GENE INFORMATION

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Gene name

MTNR1B

Synonyms

Description

Melatonin receptor 1B (HGNC Symbol)

Entrez gene summary

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q14.3

Chromosome location (bp)

92702886 - 92718232

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000134640 (version 75.37)

Entrez gene

4544

UniProt

P49286 (UniProt - Evidence at protein level)

neXtProt

NX_P49286

Antibodypedia

MTNR1B antibodies
 

PROTEIN VIEW

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MTNR1B-001
 
MTNR1B-002
 
MTNR1B-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MTNR1B-001 ENSP00000257068
ENST00000257068
P49286
Show all »
Show » Show » 362 40.2 No 7
MTNR1B-002 ENSP00000436101
ENST00000532482
E9PR36
Show all »
Show » Show » 79 8.3 No 1
MTNR1B-003 ENSP00000433573
ENST00000528076
113 12.5 No 0