DSG3

GENE INFORMATION

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Gene name

DSG3 (HGNC Symbol)

Synonyms

CDHF6

Description

Desmoglein 3 (HGNC Symbol)

Entrez gene summary

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris. [provided by RefSeq, Jul 2008]

Chromosome

18

Cytoband

q12.1

Chromosome location (bp)

29027758 - 29058665

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000134757 (version 75.37)

Entrez gene

1830

UniProt

P32926 (UniProt - Evidence at protein level)

neXtProt

NX_P32926

Antibodypedia

DSG3 antibodies
 

PROTEIN VIEW

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DSG3-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DSG3-001 ENSP00000257189
ENST00000257189
P32926
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Show » Show » 999 107.5 Yes 1