GIF

GENE INFORMATION

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Gene name

GIF (HGNC Symbol)

Synonyms

IF, IFMH, INF, TCN3

Description

Gastric intrinsic factor (vitamin B synthesis) (HGNC Symbol)

Entrez gene summary

This gene is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12. Vitamin B12 is necessary for erythrocyte maturation and mutations in this gene may lead to congenital pernicious anemia. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q12.1

Chromosome location (bp)

59596741 - 59612974

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000134812 (version 75.37)

Entrez gene

2694

UniProt

P27352 (UniProt - Evidence at protein level)

neXtProt

NX_P27352

Antibodypedia

GIF antibodies
 

PROTEIN VIEW

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GIF-001
 
GIF-003
 
GIF-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GIF-001 ENSP00000257248
ENST00000257248
P27352
Show all »
Show » Show » 417 45.4 Yes 0
GIF-003 ENSP00000433196
ENST00000525058
E9PM21
Show all »
Show » 48 5.4 Yes 0
GIF-201 ENSP00000440427
ENST00000541311
P27352
Show all »
Show » Show » 392 42.7 No 0