PDGFRA

TISSUE ATLAS

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Gene description

Platelet-derived growth factor receptor, alpha polypeptide

RNA tissue category

Tissue enhanced (ovary).

Protein summary

Detected at High or Medium expression level in 11 of 81 analyzed normal tissue cell types.

Protein expression

Most normal tissues were negative. Myoepithelial cells in breast showed strong positivity. Moderate cytoplasmic positivity was observed in subtypes of cells in renal glomeruli, ovarian, endometrial stroma cells, megakaryocytes of bone marrow, and placenta.

Protein class

Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins

Predicted localization

Membrane,Secreted

Protein evidence

Evidence at protein level

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Bone marrow
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

200
100
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Skin and soft tissues
Skin
Adipose tissue
Skeletal muscle
Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland N/A
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

CAB018143