UGT2B28

GENE INFORMATION

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Gene name

UGT2B28

Synonyms

Description

UDP glucuronosyltransferase 2 family, polypeptide B28 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Two transcript variants encoding different isoforms have been found for this gene. While both isoforms are targeted to the endoplasmic reticulum, only the longer isoform appears to be active. [provided by RefSeq, May 2011]

Chromosome

4

Cytoband

q13.2

Chromosome location (bp)

70146217 - 70160768

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000135226 (version 75.37)

Entrez gene

54490

UniProt

Q9BY64 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BY64

Antibodypedia

UGT2B28 antibodies
 

PROTEIN VIEW

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UGT2B28-001
 
UGT2B28-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UGT2B28-001 ENSP00000334276
ENST00000335568
Q9BY64
Show all »
Show » Show » 529 60.9 Yes 1
UGT2B28-002 ENSP00000427399
ENST00000511240
Q9BY64
Show all »
Show » Show » 335 38.7 Yes 0