STAB2

GENE INFORMATION

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Gene name

STAB2 (HGNC Symbol)

Synonyms

DKFZP434E0321, FEEL-2, FELL, HARE, STAB-2

Description

Stabilin 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q23.3

Chromosome location (bp)

103981051 - 104160505

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000136011 (version 75.37)

Entrez gene

55576

UniProt

Q8WWQ8 (UniProt - Evidence at protein level)

neXtProt

NX_Q8WWQ8

Antibodypedia

STAB2 antibodies
 

PROTEIN VIEW

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STAB2-001
 
STAB2-002
 
STAB2-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

STAB2-001 ENSP00000373539
ENST00000388887
Q8WWQ8
Show all »
Show » Show » 2551 277 Yes 1
STAB2-002 ENSP00000449282
ENST00000549474
H0YIF3
Show all »
Show » 33 3.7 No 0
STAB2-006 ENSP00000446629
ENST00000552777
H0YHA5
Show all »
Show » 135 14.6 No 0