NMT1

GENE INFORMATION

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Gene name

NMT1 (HGNC Symbol)

Synonyms

NMT

Description

N-myristoyltransferase 1 (HGNC Symbol)

Entrez gene summary

Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 [PubMed 1570339]).[supplied by OMIM, Nov 2008]

Chromosome

17

Cytoband

q21.31

Chromosome location (bp)

43128978 - 43186384

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000136448 (version 75.37)

Entrez gene

4836

UniProt

P30419 (UniProt - Evidence at protein level)

neXtProt

NX_P30419

Antibodypedia

NMT1 antibodies
 

PROTEIN VIEW

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NMT1-001
 
NMT1-003
 
NMT1-006
 
NMT1-007
 
NMT1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NMT1-001 ENSP00000468424
ENST00000592782
P30419
Show all »
Show » Show » 496 56.8 No 0
NMT1-003 ENSP00000439263
ENST00000543908
B7Z8J4
Show all »
Show » Show » 137 15.2 No 0
NMT1-006 ENSP00000466777
ENST00000585561
Show » 88 9.5 No 0
NMT1-007 ENSP00000466827
ENST00000592654
K7EN82
Show all »
Show » Show » 72 8.2 No 0
NMT1-201 ENSP00000258960
ENST00000258960
P30419
Show all »
Show » Show » 496 56.8 No 0