IL36G

GENE INFORMATION

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Gene name

IL36G (HGNC Symbol)

Synonyms

IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1

Description

Interleukin 36, gamma (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]

Chromosome

2

Cytoband

q13

Chromosome location (bp)

113730780 - 113743242

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000136688 (version 75.37)

Entrez gene

56300

UniProt

Q9NZH8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NZH8

Antibodypedia

IL36G antibodies
 

PROTEIN VIEW

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IL36G-001
 
IL36G-002
 
IL36G-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IL36G-001 ENSP00000259205
ENST00000259205
Q9NZH8
Show all »
Show » Show » 169 18.7 No 0
IL36G-002 ENSP00000365672
ENST00000376489
Q9NZH8
Show all »
Show » Show » 134 14.9 No 0
IL36G-003 ENSP00000411639
ENST00000447128
C9J681
Show all »
Show » Show » 38 4.1 No 0