IL33

GENE INFORMATION

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Gene name

IL33 (HGNC Symbol)

Synonyms

C9orf26, DKFZp586H0523, DVS27, IL1F11, NF-HEV

Description

Interleukin 33 (HGNC Symbol)

Entrez gene summary

IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4; MIM 147780). IL33 is a ligand for IL33R (IL1RL1; MIM 601203), an IL1 family receptor that is selectively expressed on Th2 cells and mast cells (summary by Yagami et al., 2010 [PubMed 20926795]).[supplied by OMIM, Jan 2011]

Chromosome

9

Cytoband

p24.1

Chromosome location (bp)

6215805 - 6257983

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000137033 (version 75.37)

Entrez gene

90865

UniProt

O95760 (UniProt - Evidence at protein level)

neXtProt

NX_O95760

Antibodypedia

IL33 antibodies
 

PROTEIN VIEW

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IL33-001
 
IL33-201
 
IL33-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IL33-001 ENSP00000370842
ENST00000381434
O95760
Show all »
Show » Show » 270 30.8 No 0
IL33-201 ENSP00000394039
ENST00000417746
O95760
Show all »
Show » Show » 144 16.2 No 0
IL33-202 ENSP00000414238
ENST00000456383
O95760
Show all »
Show » Show » 228 25.9 No 0