DMRT1

GENE INFORMATION

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Gene name

DMRT1 (HGNC Symbol)

Synonyms

DMT1

Description

Doublesex and mab-3 related transcription factor 1 (HGNC Symbol)

Entrez gene summary

This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq, Jul 2008]

Chromosome

9

Cytoband

p24.3

Chromosome location (bp)

841690 - 969090

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000137090 (version 75.37)

Entrez gene

1761

UniProt

Q9Y5R6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y5R6

Antibodypedia

DMRT1 antibodies
 

PROTEIN VIEW

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DMRT1-001
 
DMRT1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DMRT1-001 ENSP00000371711
ENST00000382276
Q9Y5R6
Show all »
Show » Show » 373 39.5 No 0
DMRT1-002 ENSP00000454701
ENST00000569227
H3BN61
Show all »
Show » Show » 215 23.2 No 0