CLCA2

GENE INFORMATION

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Gene name

CLCA2 (HGNC Symbol)

Synonyms

CLCRG2

Description

Chloride channel accessory 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p22.3

Chromosome location (bp)

86889769 - 86922241

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000137975 (version 75.37)

Entrez gene

9635

UniProt

Q9UQC9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UQC9

Antibodypedia

CLCA2 antibodies
 

PROTEIN VIEW

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CLCA2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CLCA2-001 ENSP00000359596
ENST00000370565
Q9UQC9
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