LHCGR

GENE INFORMATION

? »

Gene name

LHCGR (HGNC Symbol)

Synonyms

HHG, LCGR, LGR2, LHR, ULG5

Description

Luteinizing hormone/choriogonadotropin receptor (HGNC Symbol)

Entrez gene summary

This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

p16.3

Chromosome location (bp)

48859428 - 48982880

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000138039 (version 75.37)

Entrez gene

3973

UniProt

P22888 (UniProt - Evidence at protein level)

neXtProt

NX_P22888

Antibodypedia

LHCGR antibodies
 

PROTEIN VIEW

? »
 
 
 
LHCGR-001
 
LHCGR-003
 
LHCGR-004
 
LHCGR-006
 
LHCGR-007
 
LHCGR-009
 
LHCGR-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LHCGR-001 ENSP00000294954
ENST00000294954
P22888
Show all »
Show » Show » 699 78.6 Yes 7
LHCGR-003 ENSP00000386033
ENST00000405626
E7ENI1
Show all »
Show » Show » 672 75.5 Yes 7
LHCGR-004 ENSP00000385847
ENST00000403273
E7ESK4
Show all »
Show » Show » 329 36.5 Yes 0
LHCGR-006 ENSP00000385406
ENST00000401907
E7EQB5
Show all »
Show » Show » 325 36.3 Yes 0
LHCGR-007 ENSP00000403748
ENST00000428232
H7C226
Show all »
Show » Show » 175 19.8 No 0
LHCGR-009 ENSP00000473498
ENST00000602369
R4GN57
Show all »
Show » Show » 208 23 Yes 0
LHCGR-201 ENSP00000344301
ENST00000344775
E9PDH1
Show all »
Show » Show » 637 71.7 Yes 7