GALNT6

GENE INFORMATION

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Gene name

GALNT6

Synonyms

Description

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q13.13

Chromosome location (bp)

51745031 - 51786651

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000139629 (version 75.37)

Entrez gene

11226

UniProt

Q8NCL4 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8NCL4

Antibodypedia

GALNT6 antibodies
 

PROTEIN VIEW

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 « 
 
GALNT6-001
 
GALNT6-002
 
GALNT6-003
 
GALNT6-005
 
GALNT6-007
 
GALNT6-008
 
GALNT6-009
 
GALNT6-011
 
GALNT6-012
 
GALNT6-015
 
GALNT6-016
 
GALNT6-017
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GALNT6-001 ENSP00000348668
ENST00000356317
Q8NCL4
Show all »
Show » Show » 622 71.2 Yes 0
GALNT6-002 ENSP00000444171
ENST00000543196
Q8NCL4
Show all »
Show » Show » 622 71.2 Yes 0
GALNT6-003 ENSP00000474670
ENST00000603641
S4R3S5
Show all »
Show » Show » 365 41.8 Yes 0
GALNT6-005 ENSP00000473918
ENST00000604426
S4R345
Show all »
Show » 78 9.2 Yes 0
GALNT6-007 ENSP00000473836
ENST00000605617
S4R310
Show all »
Show » 69 8.2 Yes 0
GALNT6-008 ENSP00000474101
ENST00000604381
S4R3A9
Show all »
Show » 137 15.9 Yes 0
GALNT6-009 ENSP00000474483
ENST00000605055
S4R3L4
Show all »
Show » 23 2.8 No 0
GALNT6-011 ENSP00000474515
ENST00000604847
S4R3M3
Show all »
Show » 123 14.2 Yes 0
GALNT6-012 ENSP00000474052
ENST00000603188
S4R396
Show all »
Show » 62 7.4 Yes 0
GALNT6-015 ENSP00000473948
ENST00000603563
S4R355
Show all »
Show » 55 6.6 Yes 0
GALNT6-016 ENSP00000473981
ENST00000605138
S4R370
Show all »
Show » 39 4.7 Yes 0
GALNT6-017 ENSP00000474163
ENST00000604506
S4R3L4
Show all »
Show » 23 2.8 No 0