CDH11

GENE INFORMATION

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Gene name

CDH11 (HGNC Symbol)

Synonyms

CAD11, OB

Description

Cadherin 11, type 2, OB-cadherin (osteoblast) (HGNC Symbol)

Entrez gene summary

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]

Chromosome

16

Cytoband

q21

Chromosome location (bp)

64977656 - 65160015

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000140937 (version 75.37)

Entrez gene

1009

UniProt

P55287 (UniProt - Evidence at protein level)

neXtProt

NX_P55287

Antibodypedia

CDH11 antibodies
 

PROTEIN VIEW

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CDH11-001
 
CDH11-002
 
CDH11-003
 
CDH11-004
 
CDH11-007
 
CDH11-010
 
CDH11-015
 
CDH11-016
 
CDH11-017
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDH11-001 ENSP00000268603
ENST00000268603
P55287
Show all »
Show » Show » 796 88 Yes 1
CDH11-002 ENSP00000377711
ENST00000394156
P55287
Show all »
Show » Show » 693 76.5 Yes 3
CDH11-003 ENSP00000455779
ENST00000567934
H3BQH2
Show all »
Show » Show » 222 24.7 Yes 0
CDH11-004 ENSP00000457812
ENST00000566827
H3BUU9
Show all »
Show » Show » 670 73.8 No 1
CDH11-007 ENSP00000456772
ENST00000564317
H3BSM4
Show all »
Show » 65 7.6 Yes 0
CDH11-010 ENSP00000455120
ENST00000562712
H3BP26
Show all »
Show » 54 6.1 Yes 0
CDH11-015 ENSP00000455420
ENST00000562998
H3BPQ2
Show all »
Show » 70 8.2 Yes 0
CDH11-016 ENSP00000455697
ENST00000562882
H3BQB5
Show all »
Show » 34 3.8 Yes 0
CDH11-017 ENSP00000456110
ENST00000562325
H3BR78
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Show » 22 2.4 No 0