PADI3

GENE INFORMATION

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Gene name

PADI3 (HGNC Symbol)

Synonyms

PDI3

Description

Peptidyl arginine deiminase, type III (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p36.13

Chromosome location (bp)

17575593 - 17610728

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000142619 (version 75.37)

Entrez gene

51702

UniProt

Q9ULW8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9ULW8

Antibodypedia

PADI3 antibodies
 

PROTEIN VIEW

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PADI3-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PADI3-001 ENSP00000364609
ENST00000375460
Q9ULW8
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