PROK1

GENE INFORMATION

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Gene name

PROK1 (HGNC Symbol)

Synonyms

EGVEGF, PK1, PRK1

Description

Prokineticin 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner. [provided by RefSeq, Sep 2011]

Chromosome

1

Cytoband

p13.3

Chromosome location (bp)

110993822 - 110999976

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000143125 (version 75.37)

Entrez gene

84432

UniProt

P58294 (UniProt - Evidence at protein level)

neXtProt

NX_P58294

Antibodypedia

PROK1 antibodies
 

PROTEIN VIEW

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PROK1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PROK1-001 ENSP00000271331
ENST00000271331
P58294
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