GPA33

GENE INFORMATION

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Gene name

GPA33 (HGNC Symbol)

Synonyms

A33

Description

Glycoprotein A33 (transmembrane) (HGNC Symbol)

Entrez gene summary

The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q24.1

Chromosome location (bp)

167022073 - 167059868

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000143167 (version 75.37)

Entrez gene

10223

UniProt

Q99795 (UniProt - Evidence at protein level)

neXtProt

NX_Q99795

Antibodypedia

GPA33 antibodies
 

PROTEIN VIEW

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GPA33-001
 
GPA33-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GPA33-001 ENSP00000356842
ENST00000367868
Q99795
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Show » Show » 319 35.6 Yes 1
GPA33-003 ENSP00000431195
ENST00000534512
E9PMB2
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Show » 81 9.2 No 0