FCGR2A

GENE INFORMATION

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Gene name

FCGR2A (HGNC Symbol)

Synonyms

CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2

Description

Fc fragment of IgG, low affinity IIa, receptor (CD32) (HGNC Symbol)

Entrez gene summary

This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]

Chromosome

1

Cytoband

q23.3

Chromosome location (bp)

161475220 - 161493803

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000143226 (version 75.37)

Entrez gene

2212

UniProt

P12318 (UniProt - Evidence at protein level)

neXtProt

NX_P12318

Antibodypedia

FCGR2A antibodies
 

PROTEIN VIEW

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FCGR2A-001
 
FCGR2A-002
 
FCGR2A-017
 
FCGR2A-018
 
FCGR2A-020
 
FCGR2A-021
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FCGR2A-001 ENSP00000271450
ENST00000271450
P12318
Show all »
Show » Show » 317 35 Yes 1
FCGR2A-002 ENSP00000356949
ENST00000367972
P12318
Show all »
Show » Show » 316 34.9 Yes 1
FCGR2A-017 ENSP00000476411
ENST00000459885
F5H137
Show all »
Show » 86 9.6 No 0
FCGR2A-018 ENSP00000476495
ENST00000467525
Show » Show » 190 21.5 No 0
FCGR2A-020 ENSP00000440148
ENST00000483665
F5GXY9
Show all »
Show » Show » 136 15.1 Yes 0
FCGR2A-021 ENSP00000441156
ENST00000536731
F5GX41
Show all »
Show » Show » 137 15.2 Yes 0