CDH18

GENE INFORMATION

? »

Gene name

CDH18 (HGNC Symbol)

Synonyms

CDH14, EY-CADHERIN

Description

Cadherin 18, type 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]

Chromosome

5

Cytoband

p14.3

Chromosome location (bp)

19473060 - 20575982

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000145526 (version 75.37)

Entrez gene

1016

UniProt

Q13634 (UniProt - Evidence at transcript level)

neXtProt

NX_Q13634

Antibodypedia

CDH18 antibodies
 

PROTEIN VIEW

? »
 
 
 
CDH18-001
 
CDH18-002
 
CDH18-003
 
CDH18-004
 
CDH18-005
 
CDH18-006
 
CDH18-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDH18-001 ENSP00000371710
ENST00000382275
Q13634
Show all »
Show » Show » 790 88.1 Yes 1
CDH18-002 ENSP00000425854
ENST00000511273
D6RIH8
Show all »
Show » Show » 590 65.9 Yes 1
CDH18-003 ENSP00000422138
ENST00000502796
Q13634
Show all »
Show » Show » 574 63.7 Yes 0
CDH18-004 ENSP00000424931
ENST00000506372
D6RER2
Show all »
Show » Show » 575 63.7 Yes 0
CDH18-005 ENSP00000425093
ENST00000507958
Q13634
Show all »
Show » Show » 790 88.1 Yes 1
CDH18-006 ENSP00000427383
ENST00000515257
H0YAK3
Show all »
Show » Show » 441 48.6 No 0
CDH18-201 ENSP00000274170
ENST00000274170
Q13634
Show all »
Show » Show » 790 88.1 Yes 1