CRHBP

GENE INFORMATION

? »

Gene name

CRHBP (HGNC Symbol)

Synonyms

CRF-BP, CRFBP

Description

Corticotropin releasing hormone binding protein (HGNC Symbol)

Entrez gene summary

Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q13.3

Chromosome location (bp)

76248538 - 76276983

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000145708 (version 75.37)

Entrez gene

1393

UniProt

P24387 (UniProt - Evidence at protein level)

neXtProt

NX_P24387

Antibodypedia

CRHBP antibodies
 

PROTEIN VIEW

? »
 
 
 
CRHBP-001
 
CRHBP-002
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CRHBP-001 ENSP00000274368
ENST00000274368
P24387
Show all »
Show » Show » 322 36.1 Yes 0
CRHBP-002 ENSP00000426097
ENST00000506501
D6RHH7
Show all »
Show » 238 27.1 Yes 0