DCDC2

GENE INFORMATION

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Gene name

DCDC2 (HGNC Symbol)

Synonyms

DCDC2A, KIAA1154, RU2

Description

Doublecortin domain containing 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a doublecortin domain-containing family member. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. This family member is thought to function in neuronal migration where it may affect the signaling of primary cilia. Mutations in this gene have been associated with reading disability (RD) type 2, also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2013]

Chromosome

6

Cytoband

p22.3

Chromosome location (bp)

24171984 - 24358280

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000146038 (version 75.37)

Entrez gene

51473

UniProt

Q9UHG0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UHG0

Antibodypedia

DCDC2 antibodies
 

PROTEIN VIEW

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DCDC2-001
 
DCDC2-002
 
DCDC2-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DCDC2-001 ENSP00000367715
ENST00000378454
Q9UHG0
Show all »
Show » Show » 476 52.8 No 0
DCDC2-002 ENSP00000367711
ENST00000378450
Q9UHG0
Show all »
Show » Show » 229 25.6 No 0
DCDC2-003 ENSP00000410939
ENST00000436313
Show » Show » 88 9.8 No 0