NXF3

GENE INFORMATION

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Gene name

NXF3

Synonyms

Description

Nuclear RNA export factor 3 (HGNC Symbol)

Entrez gene summary

This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

q22.1

Chromosome location (bp)

102330738 - 102348157

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000147206 (version 75.37)

Entrez gene

56000

UniProt

Q9H4D5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H4D5

Antibodypedia

NXF3 antibodies
 

PROTEIN VIEW

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NXF3-001
 
NXF3-002
 
NXF3-201
 
NXF3-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NXF3-001 ENSP00000378504
ENST00000395065
Q9H4D5
Show all »
Show » Show » 531 60.1 No 0
NXF3-002 ENSP00000404017
ENST00000427570
Show » Show » 361 41.2 No 0
NXF3-201 ENSP00000404347
ENST00000425463
B4DYS7
Show all »
Show » Show » 233 26.7 No 0
NXF3-202 ENSP00000401026
ENST00000425644
E9PE86
Show all »
Show » Show » 203 22.8 No 0