SLC5A12

GENE INFORMATION

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Gene name

SLC5A12 (HGNC Symbol)

Synonyms

MGC52019, SMCT2

Description

Solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 (HGNC Symbol)

Entrez gene summary

Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]).[supplied by OMIM, Dec 2008]

Chromosome

11

Cytoband

p14.2

Chromosome location (bp)

26688566 - 26744974

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000148942 (version 75.37)

Entrez gene

159963

UniProt

Q1EHB4 (UniProt - Evidence at transcript level)

neXtProt

NX_Q1EHB4

Antibodypedia

SLC5A12 antibodies
 

PROTEIN VIEW

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SLC5A12-001
 
SLC5A12-002
 
SLC5A12-004
 
SLC5A12-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC5A12-001 ENSP00000379326
ENST00000396005
Q1EHB4
Show all »
Show » Show » 618 67.6 No >9
SLC5A12-002 ENSP00000280467
ENST00000280467
Q1EHB4
Show all »
Show » Show » 396 44.1 No 9
SLC5A12-004 ENSP00000435053
ENST00000533617
E9PLZ7
Show all »
Show » Show » 151 16.9 Yes 2
SLC5A12-005 ENSP00000436011
ENST00000527405
G3V1E3
Show all »
Show » Show » 277 30.8 Yes 4