P4HA3

GENE INFORMATION

? »

Gene name

P4HA3 (HGNC Symbol)

Synonyms

C-P4Halpha(III)

Description

Prolyl 4-hydroxylase, alpha polypeptide III (HGNC Symbol)

Entrez gene summary

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Chromosome

11

Cytoband

q13.4

Chromosome location (bp)

73946846 - 74022702

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000149380 (version 75.37)

Entrez gene

283208

UniProt

Q7Z4N8 (UniProt - Evidence at protein level)

neXtProt

NX_Q7Z4N8

Antibodypedia

P4HA3 antibodies
 

PROTEIN VIEW

? »
 
 
 
P4HA3-001
 
P4HA3-002
 
P4HA3-003
 
P4HA3-004
 
P4HA3-006
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

P4HA3-001 ENSP00000332170
ENST00000331597
Q7Z4N8
Show all »
Show » Show » 544 61.1 Yes 0
P4HA3-002 ENSP00000433860
ENST00000524388
Q7Z4N8
Show all »
Show » Show » 257 28.7 Yes 0
P4HA3-003 ENSP00000431227
ENST00000525968
E9PM97
Show all »
Show » Show » 104 11.5 Yes 0
P4HA3-004 ENSP00000401749
ENST00000427714
B4DUD3
Show all »
Show » Show » 604 67.6 Yes 0
P4HA3-006 ENSP00000431350
ENST00000532689
H0YCC3
Show all »
Show » 61 6.9 No 0